Top 10 Healthcare Software Development Companies in 2025

Summary: Choosing the right healthcare software development company in 2025 is hard. The market is crowded. Every healthcare IT solution provider claims deep domain expertise, regulatory compliance, and scalable solutions. For healthcare decision-makers, this just adds to the confusion. Cutting through the noise becomes both necessary and exhausting.

This guide will offer the clarity you need. After an in-depth evaluation of 100+ companies based on scale, specialization, and delivery, we spotlight the most credible players: Radixweb, McKesson, Oracle Health, Epic Systems, and Cognizant, alongside other top-rated healthcare IT service providers.

There are hundreds (if not thousands!) of healthcare software development companies in the market today. They all claim the same things: Scalability, security, assured success.

But not every company is alike. In fact, ‘best’ is subjective when it comes to healthcare IT services. You don’t need a partner that has done it all. You need those who’ve done what you need and been successful at that.

So, whether you are looking for healthcare app development, a HIPAA-compliant platform, or an AI-driven healthcare software engine, this list is a practical starting point.

Anchored in real-world performance, not marketing promises.

In this list, we will walk you through the top 10 choices. You can trust them with your ideas, your business integrity, and your future.

But first...

Why the Healthcare Software Market is Booming — and Confusing

The global push for digitization is reshaping the healthcare industry. The healthcare software market (especially AI diagnostics, telemedicine, and remote patient monitoring) is forecasted to surpass $1000+ billion in the coming years.

But rapid growth comes with a trade-off: overwhelming choice.

Vendors across the spectrum claim to specialize in healthcare solutions. Some emphasize deep sector knowledge. Others tout their cross-industry agility in developing all types of healthcare software. Visit any of their websites and you’ll see polished pitches that sound... remarkably similar.

For leaders overseeing healthcare IT investments, this heightens the chances of picking the wrong partner. And the risks go far beyond technical failure. Compliance missteps, data breaches, and clinical inaccuracies can have serious consequences. Guesswork isn’t an option.

This is where a carefully curated guide can help. A resource built not on vendor claims, but on verified expertise.

Why We Created This List (and How We Stayed Unbiased)

At Radixweb, we've worked with 70+ healthcare organizations in the past two and a half decades. One question that we often hear from clients is:

“How do we know which healthcare software development company we can actually trust?”

That question is what drove the creation of this list. We want healthcare organizations to be able to select a company that meets their unique needs. In many cases, we, at Radixweb, are the best choice. But if and when we are not the right match, these are some other companies you can explore.

Important: We’ve included Radixweb in this compilation, but that's not merely because we authored this guide. It is because our work in healthcare IT gives us direct insight into the standards that matter. We’ve seen the good, the bad, and the overhyped. And we know what real delivery looks like.

Our evaluations of providers of healthcare software development services focus on measurable competencies, including:

• Compliance with critical regulations like HIPAA, GDPR, HL7, FHIR
• Hands-on experience across clinical and administrative functions
• Capacity to scale solutions from mid-sized operations to large enterprises
• Technology maturity and demonstrable delivery history
• The strength and reliability of support and partnership models

No company on this list paid for inclusion. These selections are based on tangible strengths, not sales narratives.

Top Healthcare Software Development Companies 2025

Here’s the list of 10 healthcare software companies that are setting the benchmark in 2025. The list has a mix of global leaders and specialized innovators that are driving meaningful change in healthcare IT.

1. Radixweb

Radixweb is a global healthcare software development company known for building custom, enterprise-grade solutions for hospitals, clinics, institutions, and other healthcare vendors. With over 25 years of experience, we combine deep technical skills with a strong focus on healthcare compliance. That's why we've managed to get a 98% CTO approval score and a 100% client satisfaction rate.

• Location: Frisco, Texas, USA
• Employees: 650+
• Founded: 2000
• Compliance: HIPAA, HL7, FHIR, GDPR, DICOM, ICPC-2, CDA

What sets us apart:

• We have delivered 70+ healthcare solutions across RCM, telehealth, EHR, and analytics that solve healthcare complexity.
• Our team follows a regulatory-first approach. This means we ensure that compliance is built into every product from day one.
• We're also skilled in modernizing legacy systems, migrating to SaaS, developing scalable AI-driven healthcare platforms, and driving digital transformation in healthcare.
• With our Agile software development approach, we can delivery healthcare MVPs in <16 weeks.
• We can also build secure PHI data storage with our existing data center

Work with Radixweb if you want a long-term partner to build, scale, and modernize healthcare software. With 100% precision and no compliance gaps.

Check out some of our recently completed HealthTech projects below:

• Legacy Application Modernization for a Digital Healthcare Service Company
• Modernizing Cardiac PET and SPECT Imaging Web Application
• Complete Software Product Development for a Healthcare Technology Company

2. McKesson

McKesson is one of the oldest and largest healthcare companies in the world. They provide tech, supply chain solutions, and services to hospitals, pharmacies, and health systems across North America.

• Location: Irving, Texas, USA
• Employees: 48,000+
• Founded: 1833
• Compliance: HIPAA

What sets them apart:

• They’ve built integrated tools that connect supply chain, care management, and analytics.
• Their solutions are designed for big hospital networks that need smooth operations.
• They have strong partnerships with payers and providers along with a global support network.

Work with McKesson if you are a large health org looking for solutions that connect clinical and supply chain operations.

3. Oracle Health

Oracle Health was formed after Oracle acquired Cerner. Today, Oracle Health combines cloud technology with healthcare expertise. They offer global-scale EHR, analytics, and population health solutions.

• Location: Austin, Texas, USA
• Employees: 143,000+ (Oracle)
• Founded: 1977 (Oracle)
• Compliance: HIPAA

What sets them apart

• Their EHR systems come ready with built-in data sharing and interoperability features.
• Oracle Health brings powerful analytics and population health tools to deal with large data sets.
• They’re leading some exciting work around health data cloud solutions.

Work with Oracle Health if you need a full-scale, cloud-enabled EHR and data platform.

4. Epic Systems

Epic Systems is a well-known name in healthcare IT, especially for large hospitals and health networks. Their all-in-one EHR platform is recognized for reliability, scale, and seamless integration.

• Location: Verona, Wisconsin, USA
• Employees: 12,000+
• Founded: 1979
• Compliance: HIPAA

What sets them apart:

• They offer a complete EHR package including patient portals, billing, and scheduling all in one system.
• Their Care Everywhere network makes it easier for healthcare systems to exchange data.
• Epic’s solutions are built to handle scale with some of the largest hospitals in the world relying on them.

Work with Epic Systems if you need a proven, end-to-end EHR system.

5. Cognizant

Cognizant is a global IT services company with a specialized healthcare division. They support digital transformation for healthcare payers, providers, and public health systems.

• Location: Teaneck, New Jersey, USA
• Employees: 355,000+
• Founded: 1994
• Compliance: HIPAA

What sets them apart:

• Their strength lies in helping payers with systems like claims automation and population health management.
• They know how to modernize healthcare workflows using AI and data analytics.
• They’ve worked with several Fortune 500 healthcare organizations.

Work with Cognizant if you’re looking for large-scale digital transformation across operations.

6. ModMed

ModMed is a US-based HealthTech firm that builds EHR platforms tailored to specific medical specialties. Their solutions are widely used by ambulatory practices and specialist clinics.

• Location: Boca Raton, Florida, USA
• Employees: 1,500+
• Founded: 2010
• Compliance: HIPAA

What sets them apart:

• They’ve built EHR systems specifically for specialties like dermatology, ophthalmology, and gastroenterology.
• Their platforms come with billing, practice management, and analytics built right in.
• Their software for physicians is extremely intuitive and easy to use.

Work with ModMed if you run a specialist or ambulatory practice needing tailored, easy-to-use health tech.

7. Athenahealth

Athenahealth is a cloud-native healthcare software provider serving medical practices of all sizes. Their platform combines EHR, revenue cycle management, and patient engagement tools.

• Location: Watertown, Massachusetts, USA
• Employees: 6,000+
• Founded: 1997
• Compliance: HIPAA

What sets them apart:

• Their cloud-based platform is flexible and gets updated regularly to stay current.
• They have a marketplace that lets practices easily add apps and tools that fit their needs.
• They focus a lot on network intelligence, helping practices benchmark and improve continuously.

Work with Athenahealth if you want a modern, cloud-first healthcare platform that grows with your practice.

8. Bgosoftware

Bgosoftware is a healthcare software development firm based in Bulgaria. They work mainly with pharma, life sciences, and medical research companies across Europe.

• Location: Sofia, Bulgaria
• Employees: 150+
• Founded: 2008
• Compliance: HL7, IHE, and FHIR

What sets them apart

• They’ve got solid experience in building clinical trial platforms and lab systems.
• Their team knows healthcare data standards like HL7, IHE, and FHIR inside out.
• They use agile methods, so they’re able to deliver projects faster without losing quality.

Work with Bgosoftware if you’re a European healthcare company looking for clinical-grade software delivered quickly.

9. Optimum Healthcare IT

Optimum Healthcare IT is a healthcare consulting firm that helps provider networks implement and improve EHR systems. They also support training, IT strategy, and workflow optimization.

• Location: Jacksonville Beach, Florida, USA
• Employees: 1,000+
• Founded: 2012
• Compliance: HIPAA

What sets them apart:

• They’re experts in working with EHR platforms like Epic, Oracle Cerner, and Meditech.
• Their teams don’t just implement systems but also offer training and ongoing support.
• They help providers streamline workflows to get the most from their EHR investments.

Work with Optimum Healthcare IT if you need end-to-end help with EHR implementation.

10. Empeek

Empeek is a healthcare software company that helps digital health startups build HIPAA-compliant apps. Their teams work from the US and Ukraine, with a focus on mobile and web solutions.

• Location: New York, USA / Ukraine
• Employees: 100+
• Founded: 2015
• Compliance: HIPAA

What sets them apart:

• They build solutions for remote patient monitoring and the Internet of Medical Things (IoMT).
• Their pricing and engagement models are designed to fit startup budgets.
• They bring strong regulatory expertise to help startups stay compliant from the start.

Work with Empeek if you need a fast, compliant app for connected healthcare solutions.

How To Choose A Healthcare Software Development Company

You’ve got the list. But how do you figure out which healthcare software development company is actually right for you?

Not every vendor will understand your vision. Not every vendor can match your scale. Not every vendor will think and act alike.

So, you need a partner who:

• Gets your priorities
• Knows the regulations inside out
• Can build something that grows with your business.

Here are 5 simple factors to consider before your hire a healthcare software developer:

1. Compliance & Security

If your software handles patient data, there’s no room for compromise. You need HIPAA-compliant software development companies that take security seriously.

Check if they’ve passed proper security audits. Ask if they use solid encryption standards. And make sure they’re willing to sign a Business Associate Agreement.

Healthcare data is sensitive. Your tech partner must treat it like it is.

Also Read: HIPAA-Compliance Checklist for Software Development

2. Customization & Scale

Healthcare is rarely simple. Off-the-shelf tools often can’t handle real-world workflows. Nor do they connect well with legacy systems. Custom software is the future of the healthcare industry.

Need something built just for you? Go with custom healthcare software development companies. They’ll help you create solutions that actually fit your processes, not the other way around.

3. Domain Expertise

There’s no such thing as a generic healthcare solution. Running a hospital, managing clinical trials, and handling insurance all come with different challenges. And you need a partner who can help you navigate these healthcare challenges with ease.

So, pick a vendor with domain expertise in your specific space. A company that knows your world will build better, faster, and more reliably.

4. Innovation Focus

If your roadmap includes AI, analytics, or connected care, you’ll need a partner who can bring those technologies to life.

Look for AI healthcare software development companies or Healthcare SaaS development companies who’ve done it before. Not those learning on the job.

AI is transforming healthcare. You’ll want someone who can help you lead the change, not barely keep up with healthcare tech trends.

5. Delivery and Support Model

The project isn’t done when the software goes live. The real work starts after.

Work with digital health software development agencies that stick around to support you. You’ll need help with:

• Maintenance
• System performance
• Security patches, and
• Staying on top of changing regulations.

Good partners won’t disappear after deployment but stick around for long.

Radixweb: Engineering Better Healthcare OutcomesAt Radixweb, we’ve worked on over 70 healthcare projects. We’ve built patient portals, EHR systems, AI analytics tools, and connected care platforms.We’re known as one of the best companies for custom healthcare software solutions because we focus on what matters:- Solid engineering expertise- Compliance built in from the start- Solutions designed for real peopleWe help clients reduce risks, prevent project delays, and deliver outcomes that improve operations.When you work with us, you’re not just getting software. You’re getting a tech partner who’ll walk the journey with you. Let’s connect and see what’s possible.